Active Pharmaceutical Ingredients (APIs)

  • Rebamipide

    • API Product   :   

      Rebamipide

    • CEP   :   

      -

    • WCC   :   

      -

    • Therapeutic Use    :   

      Antacids, antiflatulents and anti-ulcerants

    • Originator   :   

      Otsuka pharmaceutical Co

    • CAS No.    :   

      90098-04-7

    • Trade Name.   :   

      Mucosta , Rebagen , Rebagit

    • Molecular Weight   :   

      370.786 g/mol

    • Molecular Formula   :   

      C19H15ClN2O4

    Application

    Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, is used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2.

    General Description

    Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, is used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. Rebamipide is used in a number of Asian countries including Japan (marketed as Mucosta), South Korea, China[1] and India (where it is marketed under the trade name Rebagen). It is also approved in Russia under the brand name Rebagit.[2] It is not approved by the Food and Drug Administration for use in the United States.