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Active Pharmaceutical Ingredients (APIs)
  • Quinine HCI

    • API Product   :   

      Quinine HCI

    • CEP   :   


    • WCC   :   


    • Therapeutic Use    :   


    • Originator   :   


    • CAS No.    :   


    • Trade Name.   :   


    • Molecular Weight   :   

      324.42 g/ mol

    • Molecular Formula   :   



    Quinine HCl is an alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

    General Description

    Quinine is a medication used to treat malaria and babesiosis.[2] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.[2][3] While used for restless legs syndrome, it is not recommended for this purpose due to the risk of side effects.[2] It can be taken by mouth or used intravenously.[2] Malaria resistance to quinine occurs in certain areas of the world.[2] Quinine is also the ingredient in tonic waterthat gives it its bitter taste.[4] Common side effects include headache, ringing in the ears, trouble seeing, and sweating.[2] More severe side effects include deafness, low blood platelets, and an irregular heartbeat.[2] Use can make one more prone to sunburn.[2] While it is unclear if use during pregnancy causes harm to the baby, use to treat malaria during pregnancy is still recommended.[2] Quinine is an alkaloid, a naturally occurring chemical compound.[2] How it works as a medicine is not entirely clear.

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