Active Pharmaceutical Ingredients (APIs)

  • Quetiapine Fumarate

    • API Product   :   

      Quetiapine Fumarate

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Psycholeptics

    • Originator   :   

      AstraZeneca

    • CAS No.    :   

      111974-69-7

    • Trade Name.   :   

      SEROQUEL

    • Molecular Weight   :   

      383.5099 g/mol

    • Molecular Formula   :   

      C21H25N3O2S

    Application

    This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type).

    General Description

    Quetiapine, sold under the trade name Seroquel among others, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.[6][7] It is also used as a sleep aid due to its sedating effect, but this use is not recommended.[8] It is taken by mouth.[6] Common side effects include sleepiness, constipation, weight gain, and dry mouth.[6] Other side effects include low blood pressure with standing, seizures, a prolonged erection, high blood sugar, tardive dyskinesia, and neuroleptic malignant syndrome.[6] In older people with dementia, its use increases the risk of death.[6] Use in the third trimester of pregnancy may result in a movement disorder in the baby for some time after birth.[6] Quetiapine is believed to work by blocking a number of receptors including serotonin and dopamine.