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Active Pharmaceutical Ingredients (APIs)
  • Pregabalin

    • API Product   :   

      Pregabalin

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Psycholeptics; Drugs used in diabetes; Analgesics; Anti-Epileptics

    • Originator   :   

      PFIZER

    • CAS No.    :   

      148533-50-8

    • Trade Name.   :   

      LYRICA

    • Molecular Weight   :   

      159.229 g/mol

    • Molecular Formula   :   

      C8H17NO2

    Application

    Pregabalin is used to treat pain caused by fibromyalgia, or nerve pain in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), orspinal cord injury. Pregabalin is also used with other medications to treat partial onset seizures in adults and children who are at least 4 years old.

    General Description

    Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.[10][11][12] It is a gabapentinoid and acts by inhibiting certain calcium channels.[13][14] Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.[15] Some off-label uses of pregabalin include restless leg syndrome,[16] prevention of migraines,[17] anxiety disorders,[17]and alcohol withdrawal.[18] When used before surgery, there have been varying accounts of its perioperative analgesia effects, specifically as it relates to chronic pain.[19] However, some suggest that pregabalin improves postoperative analgesia compared with placebo, at the expense of increased sedation and visual disturbances.

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