Pregabalin
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API Product :
Pregabalin
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CEP :
-
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WCC :
?
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Therapeutic Use :
Psycholeptics; Drugs used in diabetes; Analgesics; Anti-Epileptics
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Originator :
PFIZER
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CAS No. :
148533-50-8
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Trade Name. :
LYRICA
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Molecular Weight :
159.229 g/mol
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Molecular Formula :
C8H17NO2
Application
Pregabalin is used to treat pain caused by fibromyalgia, or nerve pain in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), orspinal cord injury. Pregabalin is also used with other medications to treat partial onset seizures in adults and children who are at least 4 years old.
General Description
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.[10][11][12] It is a gabapentinoid and acts by inhibiting certain calcium channels.[13][14] Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.[15] Some off-label uses of pregabalin include restless leg syndrome,[16] prevention of migraines,[17] anxiety disorders,[17]and alcohol withdrawal.[18] When used before surgery, there have been varying accounts of its perioperative analgesia effects, specifically as it relates to chronic pain.[19] However, some suggest that pregabalin improves postoperative analgesia compared with placebo, at the expense of increased sedation and visual disturbances.