Product Name   :    Metformin HCI 70.00% SR DC Granules
Dosage Form   :    Tablets
Dose   :    500/100/850/1000mg
Reference Product   :    SukkarTO
API : DMF; Dossier — CTD   :    Available
Originator   :    Bayer
Metformin hydrochloride works by improving the body's sensitivity to insulin, allowing it to use glucose in the normal way. It is the first-line drug of choice for the treatment of type 2 diabetes, particularly in overweight and obese people and those with normal kidney function.
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatmen t of type 2 diabetes,[5][6] particularly in people who are overweight.[7] It is also used in the treatment of polycystic ovary syndrome (PCOS).[5] Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.[8][9] It is not associated with weight gain.[9] It is taken by mouth.[5] Metformin is generally well tolerated.[10] Common side effects include diarrhea, nausea and abdominal pain.[5] It has a low risk of causing low blood sugar.[5] High blood lactic acid level is a concern if the medication is prescribed inappropriately and in overly large doses.[11] It should not be used in those with significant liver disease or kidney problems.[5] While no clear harm comes from use during pregnancy, insulin is generally preferred for gestational diabetes.[5][12] Metformin is in the biguanide class.[5] It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues.