API Product   :    Neostigmine Methylsulfate
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Ophthalmologicals; Other CNS Drugs
Ophthalmologicals; Other CNS Drugs
Originator   :    Eclat Pharmaceuticals
CAS No.    :    59-99-4
Trade Name.   :    PROSTIGMIN BROM
Molecular Weight   :    223.30 g/ mol
223.30 g/ mol
Molecular Formula   :    C12H19N2O2
Neostigmine methylsulfate is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.
Neostigmine, sold under the brand name Prostigmin among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retentionwithout the presence of a blockage. It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizingtype. It is given by injection either into a vein, muscle, or under the skin. After injection effects are generally greatest within 30 minutes and last up to 4 hours. Common side effects include nausea, increased saliva, crampy abdominal pain, and slow heart rate. More severe side effects include low blood pressure, weakness, and allergic reactions. It is unclear if use in pregnancy is safe for the baby. Neostigmine is in the cholinergic family of medications. It works by blocking the action of acetylcholinesterase and therefore increases the levels of acetylcholine