Active Pharmaceutical Ingredients (APIs)

  • Montelukast Sodium

    • API Product   :   

      Montelukast Sodium

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Anti-asthma and COPD Products; Nasal Preparations

    • Originator   :   

      Merck Sharp & Dohme

    • CAS No.    :   

      158966-92-8

    • Trade Name.   :   

      SINGULAIR

    • Molecular Weight   :   

      586.184 g/mol

    • Molecular Formula   :   

      C35H36ClNO3S

    Application

    Montelukast belongs to a group of medications known as leukotriene receptor antagonists. It is used to prevent and manage asthma symptoms and to relieve the symptoms of seasonal allergies, also known as seasonal allergic rhinitis or hay fever.

    General Description

    Montelukast, sold under the trade name Singulair among others, is a medication used in the maintenance treatment of asthma.[2] It is generally less preferred for this use than inhaled corticosteroids.[2] It is not useful for acute asthma attacks.[2] Other uses include allergic rhinitis and hives of long duration.[2] It is taken by mouth.[2] Common side effect include abdominal pain, cough, and headache.[2] Severe side effects may include allergic reactions such as anaphylaxis and eosinophilia.[2]Use in pregnancy appears to be safe.[2] Montelukast is in the leukotriene receptor antagonist family of medications.[2] It works by blocking the action of leukotrieneD4 in the lungs resulting in decreased inflammation and relaxation of smooth muscle.