API Product   :    Metformin HCl
CEP   :    ¤
WCC   :    ?
Therapeutic Use    :    Cholagogues and hepatic protectors; All Other Therapeutic Products; Drugs used in diabetes; Other dermatological preparations
Cholagogues and hepatic protectors; All Other Therapeutic Products; Drugs used in diabetes; Other dermatological preparations
Originator   :    Bristol-Myers Squibb; Merck & Co; Zuellig
Bristol-Myers Squibb; Merck & Co; Zuellig
CAS No.    :    657-24-9
Trade Name.   :    GLUCOPHAGE
Molecular Weight   :    129.16364 g/mol
Molecular Formula   :    C4H11N5
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problem.
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome (PCOS). Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes. It is not associated with weight gain. It is taken by mouth. Metformin is generally well tolerated. Common side effects include diarrhea, nausea and abdominal pain. It has a low risk of causing low blood sugar. High blood lactic acid level is a concern if the medication is prescribed inappropriately and in overly large doses. It should not be used in those with significant liver disease or kidney problems. While no clear harm comes from use during pregnancy, insulin is generally preferred for gestational diabetes. Metformin is in the biguanide class. It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues.