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  • Dabigatran Etexilate 50% Pellets

    • Product Name   :   

      Dabigatran Etexilate 50% Pellets

    • Dosage Form   :   

      Capsules

    • Dose   :   

      110 mg, 150 mg

    • Therapeutic Category   :   

      Anticoagulant

    • Reference Product   :   

      PRAXADA

    • API : DMF; Dossier — CTD   :   

      Available

    • Trade Name   :   

      PRAXADA®

    • Originator   :   

      Boehringer Ingelheim

    Application

    Dabigatran is used to prevent stroke and harmful blood clots (such as in your legs or lungs) if you have a certain type of irregular heartbeat (atrial fibrillation). Dabigatran is also used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism) and to reduce the risk of them occurring again. This medication may also be used to prevent these blood clots from forming after hip replacement surgery. Dabigatran is an anticoagulant that works by blocking a certain substance (a clotting protein called thrombin) in your blood. This helps to keep blood flowing smoothly in your body.

    General Description

    "Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant medication which can be taken by mouth. It is used as an alternative to warfarin, since it does not have to be monitored by blood tests, but offers similar results in terms of efficacy for a number of conditions such as stroke prevention in atrial fibrillation and the prevention and treatment of venous thromboembolism. It is a direct thrombin inhibitor, and functions by directly inhibiting both free and fibrin-bound thrombin. Compared to warfarin it has fewer interactions with other medications and does not require regular blood tests for monitoring. The main complication of its use is an increase in the risk of bleeding. In cases of severe bleeding the action of the drug can be reversed with an antidote, idarucizumab."

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