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Active Pharmaceutical Ingredients (APIs)
  • Lidocaine Base

    • API Product   :   

      Lidocaine Base

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antiseptics and disinfectants; Anaesthetics

    • Originator   :   

      NanoCyte

    • CAS No.    :   

      137-58-6

    • Trade Name.   :   

      LIDOCAINE HCL/BENZ

    • Molecular Weight   :   

      234.34 g/mol

    • Molecular Formula   :   

      C14H22N2O

    Application

    Lidocaine, also known as lignocaine, is a medication used to numb tissue in a specific area (local anesthetic). It is also used to treat ventricular tachycardia and to perform nerve blocks.

    General Description

    Lidocaine, also known as lignocaine, is a medication used to numb tissue in a specific area (local anesthetic).[4] It is also used to treat ventricular tachycardia and to perform nerve blocks.[3][4] Lidocaine mixed with a small amount of adrenaline (epinephrine) is available to allow larger doses for numbing, to decrease bleeding, and to make the numbing effect last longer.[4] When used as an injectable, it typically begins working within four minutes and lasts for half an hour to three hours.[4][5] Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.[4] Common side effects with intravenous use include sleepiness, muscle twitching, confusion, changes in vision, numbness, tingling, and vomiting.[3] It can cause low blood pressure and an irregular heart rate.[3] There are concerns that injecting it into a joint can cause problems with the cartilage.[4] It appears to be generally safe for use in pregnancy.[3] A lower dose may be required in those with liver problems.[3] It is generally safe to use in those allergic to tetracaine or benzocaine.[4] Lidocaine is an antiarrhythmic medication of the class Ib type.[3] This means it works by blocking sodium channels and thus decreasing the rate of contractions of the heart.[3] When it is used locally as a numbing agent, local neurons cannot signal the brain.

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