General Description
Fluconazole is an antifungal medication used for a number of fungal infections.[1] This includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis versicolor.[1] It is also used to prevent candidiasis in those who are at high risk such as following organ transplantation, low birth weight babies, and those with low blood neutrophil counts.[1] It is given either by mouth or by injection into a vein.[1]
Common side effects include vomiting, diarrhea, rash, and increased liver enzymes.[1] Serious side effects may include liver problems, QT prolongation, and seizures.[1] During pregnancy it may increase the risk of miscarriage while large doses may cause birth defects.[2][1] Fluconazole is in the azole antifungal family of medication.[1] It is believed to work by affecting the fungal cellular membrane.