Active Pharmaceutical Ingredients (APIs)

  • Ezetimibe

    • API Product   :   

      Ezetimibe

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Lipid-regulating/anti-atheroma preparations

    • Originator   :   

      Merck Sharp & Dohme

    • CAS No.    :   

      163222-33-1

    • Trade Name.   :   

      ZETIA

    • Molecular Weight   :   

      409.4 g/ mol

    • Molecular Formula   :   

      C24H21F2NO3

    Application

    Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet.

    General Description

    Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin or Inegy) when statins alone do not control cholesterol. Ezetimibe is recommended as second line therapy for those intolerant of statins or unable to achieve target low-density lipoprotein (LDL) cholesterol levels on statins alone by several major medical group practice guidelines, including the American College of Cardiology.