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Active Pharmaceutical Ingredients (APIs)
  • Esomeprazole Magnesium Trihydrate

    • API Product   :   

      Esomeprazole Magnesium Trihydrate

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antacids, antiflatulents and anti-ulcerants

    • Originator   :   

      Nexium®

    • CAS No.    :   

      119141-88-77

    • Trade Name.   :   

      NEXIUM

    • Molecular Weight   :   

      345.417 g/mol

    • Molecular Formula   :   

      C17H19N3O3S

    Application

    Esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

    General Description

    Esomeprazole, sold under the brand names Nexium among others,[1] is a proton-pump inhibitor which reduces stomach acid. It is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It decreases secretion of acid through inhibition of the H+/K+-ATPase in the parietal cells of the stomach. By inhibiting the functioning of this transporter, the drug prevents formation of stomach acid.

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