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Active Pharmaceutical Ingredients (APIs)
  • Diphenhydramine HCI

    • API Product   :   

      Diphenhydramine HCI

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Topical corticosteroids; Cough And Cold Preparations; Nasal Preparations; Topical Anti-Rheumatics; Psycholeptics; Other dermatological preparations; Antiemetics and antinauseants; Anti-asthma and COPD Products; Functional gastro-intestinal disorder drugs; Ophthalmologicals; Systemic Antihistamines; All Other Therapeutic Products

    • Originator   :   

      ?Johnson & Johnson

    • CAS No.    :   

      58-73-1

    • Trade Name.   :   

      BENADRYL

    • Molecular Weight   :   

      255.355 g/mol

    • Molecular Formula   :   

      C17H21NO

    Application

    Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness.

    General Description

    Diphenhydramine is an antihistamine mainly used to treat allergies.[6] It is also used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea.[6] It is used by mouth, injection into a vein, and injection into a muscle.[6] Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.[6] Common side effects include sleepiness, poor coordination, and an upset stomach.[6] Its use is not recommended in babies.[6] There is no clear risk of harm when used during pregnancy; however, use during breastfeeding is not recommended.[7] It is a first generation H1-antihistamine and works by blocking certain effects of histamine.[6] Diphenhydramine is also an anticholinergic.

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