API Product   :    Diltiazem HCl
CEP   :    ¤
WCC   :    ?
Therapeutic Use    :    Cardiac therapy; All Other Therapeutic Products; Cerebral and peripheral vasotherapeutics; Antihypertensives; Antivaricosis/antihaemorrhoidal preparations; Calcium antagonists
Originator   :    DOV Pharmaceutical
CAS No.    :    42399-41-7
Trade Name.   :    CARDIZEM
Molecular Weight   :    414.519 g/mol
Molecular Formula   :    C22H26N2O4S
Diltiazem is used to prevent chest pain (angina). It may help to increase your ability to exercise and decrease how often you may get angina attacks. Diltiazem is called a calcium channel blocker. It works by relaxing blood vessels in the body and heart and lowers the heart rate.
Diltiazem, sold under the trade name Cardizem among others, is a calcium channel blocker used to treat high blood pressure, angina, and certain heart arrhythmias.[1] It may also be used in hyperthyroidism if beta blockers cannot be used.[1] It is taken by mouth or injection into a vein.[1] When given by injections effects typically begin within a few minutes and last a few hours.[1] Common side effects include swelling, dizziness, headaches, and low blood pressure.[1] Other severe side effects include an overly slow heart beat, heart failure, liver problems, and allergic reactions.[1] Use is not recommended during pregnancy.[1] It is unclear if use when breastfeeding is safe.[2] Diltiazem works by relaxing the smooth muscle in the walls of arteries, resulting in them opening and allowing blood to flow more easily.[1] Additionally, it acts on the heart to prolong the period until it can beat again.[3] It does this by blocking the entry of calcium into the cells of the heart and blood vessels.[4] It is a class IV antiarrhythmic.