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Active Pharmaceutical Ingredients (APIs)
  • Diltiazem HCl

    • API Product   :   

      Diltiazem HCl

    • CEP   :   


    • WCC   :   


    • Therapeutic Use    :   

      Cardiac therapy; All Other Therapeutic Products; Cerebral and peripheral vasotherapeutics; Antihypertensives; Antivaricosis/antihaemorrhoidal preparations; Calcium antagonists

    • Originator   :   

      DOV Pharmaceutical

    • CAS No.    :   


    • Trade Name.   :   


    • Molecular Weight   :   

      414.519 g/mol

    • Molecular Formula   :   



    Diltiazem is used to prevent chest pain (angina). It may help to increase your ability to exercise and decrease how often you may get angina attacks. Diltiazem is called a calcium channel blocker. It works by relaxing blood vessels in the body and heart and lowers the heart rate.

    General Description

    Diltiazem, sold under the trade name Cardizem among others, is a calcium channel blocker used to treat high blood pressure, angina, and certain heart arrhythmias.[1] It may also be used in hyperthyroidism if beta blockers cannot be used.[1] It is taken by mouth or injection into a vein.[1] When given by injections effects typically begin within a few minutes and last a few hours.[1] Common side effects include swelling, dizziness, headaches, and low blood pressure.[1] Other severe side effects include an overly slow heart beat, heart failure, liver problems, and allergic reactions.[1] Use is not recommended during pregnancy.[1] It is unclear if use when breastfeeding is safe.[2] Diltiazem works by relaxing the smooth muscle in the walls of arteries, resulting in them opening and allowing blood to flow more easily.[1] Additionally, it acts on the heart to prolong the period until it can beat again.[3] It does this by blocking the entry of calcium into the cells of the heart and blood vessels.[4] It is a class IV antiarrhythmic.

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