API Product   :    Dacarbazine*
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Antineoplastics
Originator   :    Southern Research Institute in Birmingham
CAS No.    :    4342-03-4
Trade Name.   :    DTIC-DOME
Molecular Weight   :    182.18 g/mol
Molecular Formula   :    C6H10N6O
Dacarbazine is used to treat certain types of cancer, such as skin cancer that has spread (metastatic malignant melanoma) and Hodgkin's disease. It is a cancer chemotherapy drug that is used alone or with other medications to slow or stop cancer cell growth.
Dacarbazine also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma.[1] For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin.[1] It is given by injection into a vein.[1]Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets.[1] Other serious side effects include liver problems and allergic reactions.[1] It is unclear if use in pregnancy is safe for the baby.[1] Dacarbazine is in the alkylating agent and purine analog families of medication