Active Pharmaceutical Ingredients (APIs)

  • Dacarbazine*

    • API Product   :   

      Dacarbazine*

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antineoplastics

    • Originator   :   

      Southern Research Institute in Birmingham

    • CAS No.    :   

      4342-03-4

    • Trade Name.   :   

      DTIC-DOME

    • Molecular Weight   :   

      182.18 g/mol

    • Molecular Formula   :   

      C6H10N6O

    Application

    Dacarbazine is used to treat certain types of cancer, such as skin cancer that has spread (metastatic malignant melanoma) and Hodgkin's disease. It is a cancer chemotherapy drug that is used alone or with other medications to slow or stop cancer cell growth.

    General Description

    Dacarbazine also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma.[1] For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin.[1] It is given by injection into a vein.[1]Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets.[1] Other serious side effects include liver problems and allergic reactions.[1] It is unclear if use in pregnancy is safe for the baby.[1] Dacarbazine is in the alkylating agent and purine analog families of medication