API Product   :    Dacarbazine*
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Antineoplastics
Originator   :    Southern Research Institute in Birmingham
Southern Research Institute in Birmingham
CAS No.    :    4342-03-4
Trade Name.   :    DTIC-DOME
Molecular Weight   :    182.18 g/mol
Molecular Formula   :    C6H10N6O
Dacarbazine is used to treat certain types of cancer, such as skin cancer that has spread (metastatic malignant melanoma) and Hodgkin's disease. It is a cancer chemotherapy drug that is used alone or with other medications to slow or stop cancer cell growth.
Dacarbazine also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein.Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets. Other serious side effects include liver problems and allergic reactions. It is unclear if use in pregnancy is safe for the baby. Dacarbazine is in the alkylating agent and purine analog families of medication