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Active Pharmaceutical Ingredients (APIs)
  • Clopidogrel Bisulfate

    • API Product   :   

      Clopidogrel Bisulfate

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Urologicals; Antithrombotic agents; Cardiac therapy

    • Originator   :   

      Sanofi Aventis

    • CAS No.    :   

      113665-84-2

    • Trade Name.   :   

      PLAVIX

    • Molecular Weight   :   

      321.82 g/mol

    • Molecular Formula   :   

      C16H16ClNO2S

    Application

    Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients.

    General Description

    Clopidogrel, sold as the brandname Plavix among others,[1] is an antiplatelet medication that is used to reduce the risk of heart disease and stroke in those at high risk.[2] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy).[2] It is taken by mouth.[2] Onset of effects is about 2 hours and lasts for 5 days.[2] Common side effects include headache, nausea, easy bruising, itching, and heartburn.[2] More severe side effects include bleeding and thrombotic thrombocytopenic purpura.[2] While there is no evidence of harm from use during pregnancy, such use has not been well studied.[3] Clopidogrel is in the thienopyridine-class of antiplatelets.[2] It works by irreversibly inhibiting a receptor called P2Y12 on platelets.

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