Celecoxib
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API Product :
Celecoxib
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CEP :
¤
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WCC :
?
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Therapeutic Use :
Antineoplastics; Other gynaecologicals; Analgesics; Anti-Inflammatory And Anti-Rheumatic Products
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Originator :
Monsanto
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CAS No. :
169590-42-5
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Trade Name. :
CELEBREX
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Molecular Weight :
381.373 g/mol
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Molecular Formula :
C17H14F3N3O2S
Application
This medication is a nonsteroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor, which relieves pain and swelling (inflammation). It is used to treat arthritis, acute pain, and menstrual pain and discomfort.
General Description
Celecoxib sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older.[2] Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.[3] Additionally, an 81% increase in incidence of upper gastrointestinal complications occurs, which include perforations, obstructions, or gastrointestinal bleeding as in all nonsteroidal anti-inflammatory drugs (NSAIDs).[3] In July 2015 the FDA strengthened the warning that non-aspirin NSAIDs can cause heart attacks or strokes.[4]