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Active Pharmaceutical Ingredients (APIs)
  • Zoledronic Acid

    • API Product   :   

      Zoledronic Acid

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Other Drugs For Disorders Of The Musculo-Skeletal System

    • Originator   :   

      Hospira

    • CAS No.    :   

      118072-93-8

    • Trade Name.   :   

      ZOMETA

    • Molecular Weight   :   

      272.09 g/mol

    • Molecular Formula   :   

      C5H10N2O7P2

    Application

    This medication is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Zoledronic acid is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and other types of cancer (such as breast, lung) that have spread to the bones.

    General Description

    Zoledronic acid, also known as zoledronate, is a medication used to treat a number of bone diseases.[1] This include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, and Paget’s disease of bone.[1] It is given by injection into a vein.[1] Common side effects include fever, joint pain, high blood pressure, diarrhea, and feeling tired.[1] Serious side effects may include kidney problems, low blood calcium, and osteonecrosis of the jaw.[1] Use during pregnancy may result in harm to the baby.[1] It is in the bisphosphonate family of medications.[1] It works by blocking the activity of osteoclast cells and thus decreases the breakdown of bone.

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