API Product   :    Tramadol HCI
CEP   :    -
WCC   :    ?
Therapeutic Use    :    All Other Therapeutic Products; Cough And Cold Preparations; Analgesics; Psychoanaleptics Excluding Anti-Obesity Preparations
All Other Therapeutic Products; Cough And Cold Preparations; Analgesics; Psychoanaleptics Excluding Anti-Obesity Preparations
Originator   :    Janssen Pharmaceutica
CAS No.    :    27203-92-5
Trade Name.   :    ULTRAM
Molecular Weight   :    263.381 g/mol
Molecular Formula   :    C16H25NO2
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain. When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. It is also available by injection. It may be sold in combination with paracetamol (acetaminophen) or as longer acting formulations. Common side effects include constipation, itchiness, and nausea. Serious side effects may include seizures, increased risk of serotonin syndrome, decreased alertness, and drug addiction. A change in dosage may be recommended in those with kidney or liver problems. It is not recommended in those who are at risk of suicide or in those who are pregnant. While not recommended in women who are breastfeeding, those who take a single dose should not generally stop breastfeeding. Tramadol acts by binding to the ?-opioid receptor of the neuron and is also a serotonin–norepinephrine reuptake inhibitor. It is converted in the liver to O-desmethyltramadol, an opioid with stronger binding to the ?-opioid receptor.