API Product   :    Thiotepa
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Antineoplastics
Originator   :    Sumitomo Dainippon Pharma
Sumitomo Dainippon Pharma
CAS No.    :    52-24-4
Trade Name.   :    TEPADINA
Molecular Weight   :    189.23 g/mol
Molecular Formula   :    C6H12N3PS
Thiotepa is used to treat cancer. It works by slowing or stopping the growth of cancer cells. Thiotepa is often given into the bladder to treat bladder cancer. Thiotepa is also used with other medications to prevent rejection of a stem cell transplant.
Thiotepa (INN, chemical name: N,N?,N??-triethylenethiophosphoramide) is an alkylating agent used to treat cancer. Thiotepa is an organophosphorus compound with the formula SP(NC2H4)3. It is an analog of N,N?,N??-triethylenephosphoramide (TEPA), which contains tetrahedral phosphorus and is structurally akin to phosphate. It is manufactured by heating aziridine with thiophosphoryl chloride.