Active Pharmaceutical Ingredients (APIs)

  • Thiotepa

    • API Product   :   

      Thiotepa

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antineoplastics

    • Originator   :   

      Sumitomo Dainippon Pharma

    • CAS No.    :   

      52-24-4

    • Trade Name.   :   

      TEPADINA

    • Molecular Weight   :   

      189.23 g/mol

    • Molecular Formula   :   

      C6H12N3PS

    Application

    Thiotepa is used to treat cancer. It works by slowing or stopping the growth of cancer cells. Thiotepa is often given into the bladder to treat bladder cancer. Thiotepa is also used with other medications to prevent rejection of a stem cell transplant.

    General Description

    Thiotepa (INN,[1] chemical name: N,N?,N??-triethylenethiophosphoramide) is an alkylating agent used to treat cancer. Thiotepa is an organophosphorus compound with the formula SP(NC2H4)3.[2] It is an analog of N,N?,N??-triethylenephosphoramide (TEPA), which contains tetrahedral phosphorus and is structurally akin to phosphate. It is manufactured by heating aziridine with thiophosphoryl chloride.