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Active Pharmaceutical Ingredients (APIs)
  • Theobromine

    • API Product   :   


    • CEP   :   


    • WCC   :   


    • Therapeutic Use    :   

      Psychoanaleptics Excluding Anti-Obesity Preparations; Respiratory System; Cough And Cold Preparations; Other dermatological preparations; Cerebral and peripheral vasotherapeutics; Diuretics; Cardiac therapy; Anti-asthma and COPD Products

    • Originator   :   


    • CAS No.    :   


    • Trade Name.   :   


    • Molecular Weight   :   

      180.164 g/mol

    • Molecular Formula   :   



    Theobromine, or 3, 7-Dimethylxanthine, is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle.

    General Description

    Theobromine, formerly known as xantheose,[1] is a bitter alkaloid of the cacao plant, with the chemical formula C7H8N4O2.[1] It is found in chocolate, as well as in a number of other foods, including the leaves of the tea plant, and the kola nut. It is classified as a xanthine alkaloid,[2] others of which include theophylline and caffeine.[1] The compounds differ in that caffeine has an extra methyl group (see under Pharmacology section). Despite its name, the compound contains no bromine—theobromine is derived from Theobroma, the name of the genus of the cacao tree (which itself is made up of the Greek roots theo ("god") and broma ("food"), meaning "food of the gods"[3]) with the suffix -ine given to alkaloids and other basic nitrogen-containing compounds.[4] Theobromine is a slightly water-soluble (330 mg/L[5]), crystalline, bitter powder. Theobromine is white or colourless, but commercial samples can be yellowish.[6] It has an effect similar to, but lesser than, that of caffeine in the human nervous system, making it a lesser homologue. Theobromine is an isomer of theophylline, as well as paraxanthine. Theobromine is categorized as a dimethyl xanthine.

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