Active Pharmaceutical Ingredients (APIs)

  • Rosuvastatin Calcium

    • API Product   :   

      Rosuvastatin Calcium

    • CEP   :   

      ¤

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Lipid-regulating/anti-atheroma preparations; Cardiac therapy

    • Originator   :   

      AstraZeneca

    • CAS No.    :   

      287714-41-4

    • Trade Name.   :   

      CRESTOR

    • Molecular Weight   :   

      481.539 g/ mol

    • Molecular Formula   :   

      C22H28FN3O6S

    Application

    Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver.

    General Description

    Rosuvastatin, sold under the tradename Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids.[3] It recommended to be used together with dietary changes, exercise, and weight loss.[3] It is taken by mouth.[3] Common side effects include abdominal pain, nausea, headaches, and muscle pains.[3] Serious side effects may include rhabdomyolysis, liver problems, and diabetes.[3] Use during pregnancy may harm the baby.[3] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver that plays a role in producing cholesterol.