API Product   :    Abiraterone Acetate*
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Psycholeptics; Cytostatic Hormone Therapy
Psycholeptics; Cytostatic Hormone Therapy
Originator   :    Johnson and Johnson
Johnson and Johnson
CAS No.    :    154229-18-2
Trade Name.   :    Zytiga
Molecular Weight   :    391.555 g/mol
Molecular Formula   :    C26H33NO2
Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.
Abiraterone, developmental code name CB-7598, also known as 17-(3-pyridyl)androsta-5,16-dien-3-ol, is a synthetic, steroidal CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, an ester and prodrug of abiraterone. A metabolite of abiraterone has been found to act as an agonist of the androgen receptor, and may antagonize the clinical effectiveness of abiraterone acetate.