Active Pharmaceutical Ingredients (APIs)

  • Abiraterone Acetate*

    • API Product   :   

      Abiraterone Acetate*

    • CEP   :   

      -

    • WCC   :   

      TEst

    • Therapeutic Use    :   

      Psycholeptics; Cytostatic Hormone Therapy

    • Originator   :   

      Johnson and Johnson

    • CAS No.    :   

      154229-18-2

    • Trade Name.   :   

      Zytiga

    • Molecular Weight   :   

      391.555 g/mol

    • Molecular Formula   :   

      C26H33NO2

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    Application

    Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.

    General Description

    Abiraterone, developmental code name CB-7598, also known as 17-(3-pyridyl)androsta-5,16-dien-3-ol, is a synthetic, steroidal CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, an ester and prodrug of abiraterone. A metabolite of abiraterone has been found to act as an agonist of the androgen receptor, and may antagonize the clinical effectiveness of abiraterone acetate.