Sr NoAPI NameName of the ImpurityCAS NumberIMP Identification
1Abacavir([(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol)124752-25-6Descyclopropyl IMP
2Abacavir({(1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol)141271-11-6Trans IMP
3Abacavir(N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine)O-Pyrimidine derivative IMP
4Abacavir(9-[(1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl]-N6-cyclopropyl-9H-purine-2,6-diaminet-Butyl derivative IMP
5Abacavir{(1R,4S)-4-[2-Amino-6-(cyclopropylamino)
-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
Enantiomeric IMP
6Abacavir2-Amino-9-((1R,4S)-4-(hydroxymethyl)cyclopent-2-enyl)-5H-purin-6(9H)-oneDegradation IMP
7Abacavir(1S,4R)-4-(2-Amino-6-chloro-8H-purin-9-yl)cyclopent-2-enyl)methanol-
8Abacavir((1R,3S0-3-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopentyl)methanolDihydro IMP
9AbacavirN6-Cyclopropyl-9H-purine-2,6-diamine120503-69-7Cyclopropyl
Diaminopurine IMP
10Abacavir((1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl)methanol124752-25-6Amino IMP
11AcyclovirAceticacid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)
-ethyl ester
N/AEP IMP-A
(Valacyclovir EP IMP-I)
12Alfuzosin
HCl
N?[3?[(4?Amino?6,7?dimethoxyquinazolin?2?yl)methylamino]propyl]formamideIMP-E
13Alfuzosin
HCl
2-Chloro-6,7-dimethoxyquinazolin-4-
amine
23680-84-4IMP-B
14Alfuzosin
HCl
N-(4-Amino-6,7-dimethoxyquinazolin-2-
yl)-N-methylpropane-1,3-diamine
IMP-D
15Alfuzosin
HCl
N-[3-[4-Amino-6,7-dimethoxy-quinazolin-2-yl)methylamino]
propyl]furan-2-carboxamide
98902-29-5IMP-A
16Alfuzosin
HCl
N-(3-(4-Amino-6,7-dimethoxy
quinazolin-2-ylamino)propyl)-tetrahydro-N-methylfuran-2-carboxamide
72104-34-8IMP-C
17AliskrineN-(2-(2-Cyano-2-methylpropyl
carbamoyl)-2-methylpropyl)-7-(3-(3-methoxypropoxy)-4-methoxy
benzyl)-5-azido-4-hydroxy-2-isopropyl-8-methylnonanamide
IMP
18Almotriptan4-(Pyrrolidine-1-sulfonylmethyl)-phenylamine
19Almotriptan[4-(Pyrrolidine-1-sulfonylmethyl)-phenyl]-hydrazine HCl
20Ambrisentan2-(2,2-Diphenylvinyloxy)-4,6-dimethylpyrimidineN/ADecarboxylated IMP
21Amlodipine3?Ethyl 5?methyl 2?[(2?amino
ethoxy)methyl]?4?(2?chloro
phenyl)?6?methylpyridine? 3,5?dicarboxylate
113994-41-5IMP-D(EP)
22Amlodipine3?Methyl 5?methyl 4?(2?chloro
phenyl)?6?methyl?2?[[2?[(2?amino
ethoxy)methyl]?1,4?dihydropyridine?3,5?dicarboxylate
140171-66-0IMP-F(EP)
23Amlodipine3?Ethyl 5?methyl (4RS)?4?
(2?chlorophenyl)?6?methyl?2?[[2?[[2?(methylcarbamoyl)benzoyl]
amino]ethoxy]methyl]?1,4?dihydropyridine?3,5?dicarboxylate
721958-72-1EP IMP-B
24Aripiprazole7-(4-Bromobutoxy)-3,4-dihydroquinolin-2(1H)-one129722-34-5Bromo IMP
25Aripiprazole7-(4-(4-(2,3-Dichlorophenyl)
piperazin-1-yl)butoxy)-1-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-3,4-dihydroquinolin-2(1H)-one
N/ADimer IMP
26Aripiprazole7-(4-(4-(2,3-Dichlorophenyl)
piperazin-1-yl)butoxy)quinolin-2(1H)-one
129722-25-4IMP-E
(USP RC-G)
27Aripiprazole7-(4-(4-(2-Chlorophenyl)
piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one
N/AIMP-C
28Ariprazole7-(4-(4-(3-Chlorophenyl)
piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one
203395-82-8IMP-D
29Atomoxetin HCl(R)-N-Methyl-3-phenoxy-3-phenylpropan-1-amineEP IMP-A
(Desmethyl IMP)
30Atorvastatin(3R,5R)-7-[5-(4-Fluorophenyl)-3-isopropyl-2-oxo-4-phenyl-3-(phenylcarbamoyl)-2,3-dihydro-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid.
USP
Pyrrolidone Analog
31Atorvastatin(3R,5R)-Methyl 7-(3-(phenylcar
bamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1Hpyrrol-1-yl)-3,5-dihydroxyheptanoate
345891-62-5Methyl Ester IMP
32Atorvastatin(3S,5S)-7-(3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1Hpyrrol-1-yl)-3,5-dihydroxyheptanoic acidEnantiomer IMP
33Atorvastatin(3R,5R)-7-(3-(Phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl)-3,5-dihydroxy
heptanoic acid
433289-83-9Desfluoro IMP
34Atorvastatin(3S,5R)-7-(3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic
Acid
N/ADiastereomer IMP
35Atorvastatin(3R,5R)-7-[3-(Phenylcarbamoyl)-4,5-bis(4-fluorophenyl)- 2-isopropyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt)N/ADifluoro IMP
36Atorvastatin3-(4-Fluorobenzoyl)-2-(2-methyl-1-oxopropyl)-N,3-diphenyloxiranecarboxamide148146-51-4Epoxide EP IMP-D
37Atovaquone2-((1R,4R)-4-(4-Chlorophenyl)
cyclohexyl)-3-oxo-3H-indene-1-carboxylic acid
EP IMP-A
(USP Indene isomer)
38Atovaquone2-((1S,4S)-4-(4-Chlorophenyl)
cyclohexyl)-3-hydroxy
naphthalene-1,4-dione
USP RC – A
(EP IMP-B)
39Atovaquone2-((1R,4R)-4-(4-Chlorophenyl)
cyclohexyl)-3-methoxynaphthalene-1,4-dione
EP IMP-D
(USP methoxy Atovaquone)
40Bromazepam(2-Amino-5-bromophenyl)(pyridin-2-yl)methanone1563-56-0IMP-A(EP)
41Bromazepam3-Amino-6-bromo-4-(pyridin-2-yl)quinolin-2(1H)-oneN/AIMP-D(EP)
42Bromazepam3-Amino-6-bromo-4-(pyridin-2-yl)quinolin-2(1H)-oneN/AIMP-D(EP)
43Capecitabine2-Methylbutyl 1-((2S,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-ylcarbamateIMP-1
44CapecitabineIsopentyl 1-((2S,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-ylcarbamateIMP-2
45Carvedilol(R)-1-(9H-Carbazol-4-yloxy)-3-(N-(2-(2-methoxyphenoxy)ethyl)-N-benzylamino)propan-2-ol72955-94-3EP IMP-C
46Carvedilol4 – (Oxiran – 2-yl-methoxy) – 9H – carbazole51997-51-4IMP-D
47Carvedilol1-[9-[2-Hydroxy-3 {[2-(2-methoxyphenoxy) ethyl] amino} propyl- [9H – carbazol-4-yloxy]-3-[2- (2-methoxyphenoxy) ethyl] amino] propan-2-ol1198090-73-1IMP-A
48Carvedilol1,1'- [[2-(2-Methoxyphenoxy) ethyl] nitrilo] bis – [3-(9H-carbazol-4yloxy) propan-2-ol)]918903-20-5IMP-B
49Carvedilol2 – (2- Methoxyphenoxy) ethanamine1836-62-0IMP-E
50Carvedilol1 – [Bis [2-(2-methoxyphenoxyethyl [amino]-3-[9H – carbazol – 4 – yloxy) propan – 2 – ol]N/AIMP-E
51Celecoxib4-Methyl acetophenone122-00-9
52Citalopram(1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)(4-fluorophenyl)methanone4-Phenylketo IMP
53Citalopram4-(Dimethylamino)-1-((R)-1-(3-
(dimethylamino)propyl)-1-(4-fluorophenyl)-
1,3-dihydroisobenzofuran-5-yl)butan-1-one
Impurity – EP IMP-G (Dimethylamino
propyl keto) IMP
54Citalopram1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-3-oxoisobenzofuran-5-carbonitrile HBrOxo IMP
55CitalopramCitalopram HBr N-oxideN-Oxide IMP
56Citalopram1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic acidAcid IMP
57CitalopramMethyl-1-(3-(dimethylamino)
propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylate
Methyl ester IMP
58Citalopram1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxamideCarboxamide IMP
59Citalopram3-(5-Chloro-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)-N,N-dimethylpropan-1-amineChloro IMP
60Clopidogrel(2S)(+)-(2-Chlorophenyl)-2(6.7-dihydro-4H-thieno- [3,2-c] pyridine-5-yl)-2-acetic acid144457-28-3IMP-A (USP RC-A)
61DesloratadineIso Desloratadine183198-49-4IMP-B
62Desvenlafaxine1-(1-(4-(Benzyloxy)phenyl)-2-(dimethylamino)ethyl)cyclohexanol93413-61-7Dimethylamino
Benzyloxyphenyl IMP
63Desvenlafaxine4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate386750-22-7Working standard
64Dexlansoprazole2-((3-Methyl-4-(methylsulfonyl)pyridin-2-yl)methylsulfonyl)-1H-benzo
[d]imidazole
DXL-II Sulfone IMP
65Dexlansoprazole2-((4-(2,2,2-Trifluoroethoxy)-3-methylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole
S-Isomer IMP
66Dexlansoprazole2,3-Dimethyl-4-(methylsulfonyl)pyridineDeschloro IMP of PSM
67Dexlansoprazole2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole 1’-oxide.N/ASulfone N-Oxide IMP
68Duloxetine(1S)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol116539-55-0USP IMP-B
69Duloxetine2-[(1RS)-3-(Methylamino)-1-(thiophen-2-yl)propyl]naphthalen-1-olUSP IMP-E
70Efavirenz((S,E)-6-Chloro-4-(2-Cyclopro
pylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one)
440124-96-9Ethylene IMP
71Efavirenz(S)-(-)-6-Chloro-4-(cyclopropyl
ethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
154598-52-4Enantiomer IMP
72EfavirenzEfavirenz aminoalcohol methyl carbamate211563-40-5USP Amino alcohol methylcarbamate
(WHO-IMP-H)
73Emtricitabine5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dioneDesamino IMP
74Emtricitabine4-Amino-5-fluoro-1-((5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-oneDiastereomer IMP
75Eprosartan2-((Thiophen-2-yl)methyl)malonic acid4475-24-5Diacid IMP
76Eprosartan3-(Thiophen-2-yl)propionic acidDecarboxylated IMP
77Eprosartan4-((2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl)benzoic acidChloroimidazole Benzoic Acid IMP
78Escitalopram3-Dimethylamino-1-propyl bromide
79Esomeprazole5-Methoxy-1H-benzimidazole-2-thiol37052-78-1IMP-A
80Esomeprazole2-[(RS)-[(3,5-Dimethylpyridin-2-
yl)methyl]sulphinyl]-5-methoxy-1H-benzimidazole
IMP-B
81Esomeprazole5-Methoxy-2-[[(4-methoxy-3,5-
dimethylpyridin-2-yl)methyl]-sulphanyl]-1H-benzimidazole (Ufiprazole)
73590-85-9IMP-C
82Esomeprazole5-Methoxy-2-[[(4-methoxy-3,5-
dimethylpyridin-2-yl)methyl]sulphonyl]-
1H- benzimidazole (Omeprazole
Sulphone)
88546-55-8IMP-D
83Esomeprazole4-Methoxy-2-[[(RS)-(5-methoxy- 1Hbenzimidazol-2-yl)
sulphinyl]methyl]-3,5-dimethyl
pyridine 1-Oxide (Omeprazole
N-Oxide
176219-04-8IMP-E
84Fluindione(E)-3-(4-Fluorobenzylidene)
isobenzofuran-1(3H)-one
Benzylidene IMP
85Fluindione2-(4-Methoxyphenyl)-2H-indene-1,3-dione117-37-3Methoxy IMP
86Gatifloxacin1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acidPiperazine IMP
87Hyydroxyzine HCl1. RS)-1-[(4 Chlorophenyl)phenylmethyl]piperazine303-26-4IMP-A
88Hyydroxyzine HCl2. 2-[-2-[4-(Diphenylmethyl)piperazin-1-yl]ethoxy]ethanol (Decloxizine)3733-63-9IMP-B
89IloperidoneIloperidone N-oxide impurityN/AN-Oxide IMP
90Iloperidone6-Fluoro-3-(piperidin-4-yl)benzo[d]isoxazole HCl84163-13-3Benzisoxazole IMP
91Iloperidone1-(4-(3-Bromopropoxy)-3-methoxyphenyl)ethanone3245-49-6Bromo IMP
92Imatinib4-(Chloromethyl)-N-[(3-(chloromethyl)(4-(pyridine-3-yl) pyrimid in-2-yl)amino)-4-methyl phenyl] benzamideIMP-B
93Imatinib4-[(4-Methyl-4-oxido-piperazinyl) methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-3-yl)amino]phenyl]benazamide
N-Oxide IMP
94ImatinibN-(4-Methyl-3-(4-methyl-3-yl-pyrimidin-2-ylamino)-phenyl)-4-chloromethylbenzamide
95Imatinib4-[(4-Methyl-1-Piperazinyl)
methyl]-N-[4-Methyl-3-[4-(3-Pyridinyl)-2-Pyrimidinyl] chloromethyl amino] phenyl]benzamide
96Lamivudine(2R-cis)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid173829-09-9Carboxylic Acid IMP
97Lamivudine4-Amino-1-(2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-oneDiastereomer IMP
98Lamotrigene3-Amino-6-(2,3-dichlorophenyl)-1,2,4-trazin-5(4H)-one252186-78-0IMP-A
99LevetiracetamMethyl 2-(2-oxopyrrolidin-1-yl)
butanoate
Methyl Ester IMP
100LevofloxacinLevofloxacin-N-oxideN/AN-Oxide IMP
101LevofloxacinMethyl 9,10-difluoro-3,5,6,7-tetrahydro-3-methyl-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylateEster IMP
102Levofloxacin(R)-9,10-Difluoro-3,7-dihydro-3-methyl-7-oxo-2H-[1,4]oxazino
[2,3,4-ij]quinoline-6-carboxylic acid
R-Levo Acid IMP
103Levofloxacin(S)-3,7-Dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acidDesfluoro IMP
104Levofloxacin(R)-10-(2-Aminoethylamino)-9-fluoro-3,7-dihydro-3-methyl-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acidEthylene Diamine IMP
105Linezolid(5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone(Linazolid -A)IMP-A
106LinezolidN-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-ethane thioamideIMP-B
107Linezolid(-)-(S)-5-(Aminomethyl)-3-(3-fluoro-4-morpholinophenyl)
oxazolidin-2-one
IMP-C
108Lisinopril(2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-cyclohexylpropyl]amino] hexanoyl]pyrrole-2-carboxylic acid
1132650-67-9IMP-F
109Olanzapine2-Methyl-4-(4-methyl-4-oxido-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine174794-02-6N-Oxide IMP
110Olanzapine2-Methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine161696-76-0Piperazine IMP
111Olanzapine2-Methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine719300-59-1IMP-C
112Omeprazole6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole176219-04-8N-Oxide IMP
113Omeprazole5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfonyl]-
1H-benzimidazole
158812-85-2Sulfone N-oxide IMP
114Oseltamivir(3R,4R,5S)-Ethyl 4-(N-tert-butylacetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate HClTert – Butyl acetamide
HCl Salt IMP
115Oseltamivir(3aR,4R,7aR)-6-(Ethoxycarbonyl)-3a,4,5,7a-tetrahydro-2,2-dimethylbenzo[d][1,3]dioxol-4-yl methanesulfonateMesyl Shikmate IMP
116OseltamivirMethyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylateWHO IMP-D (Methyl ester)
117Paliperidone3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one761460-08-6N-Oxide IMP
118Paliperidone3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8-dihydro-2-methyl-6H-pyrido[1,2-a]pyrimidine-4,9-dione1189516-65-1Keto IMP
119Paroxetin((3S,4R)-4-(4-Fluorophenyl)
piperidin-3-yl)methanol
EP IMP-I
120Paroxetin((3S,4R)-1-Benzyl-4-(4-fluorophenyl)piperidin-3-yl)methanolEP IMP-H
121Paroxetin
4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine
1012886-75-7USP RC-E (EP IMP-G)
122Prasugrel5-Acetyl-4,5,6,7-tetrahydro
thieno[3,2-c]pyridin-2-yl acetate
Diacetyl IMP
123Quetiapine Fumarate2-[2-(4-Dibenzo [b,f][1,4]thia
zepin11-yl-1-iperazinyl)- ethanol
Hydroxy IMP
124Quetiapine FumarateDibenzo[b,f][1,4]thiazepine-11(10H)oneRC-G IMP
125Rizatriptan2-(5-((5-((1H-1,2,4-Triazol-1-yl)methyl)-3-(2-(dimethylamino)ethyl)-1H-indol-2-yl)methyl)-1H-indol-3-yl)-N,N-dimethylethanamine benzoate1016900-25-6
126Rizatriptan1-(4-((1H-1,2,4-Triazol-1-yl)methyl)phenyl)hydrazine HCl
127Rizatriptan4,4-Bis(5-((1H-1,2,4-triazol-1-yl)methyl)-3-(2-(dimethylamino)ethyl)-1H-indol-2-yl)-N,N-dimethylbutan-1-amine1135479-44-52,2-Dimer IMP
128Rizatriptan4-(5-((1H-1,2,4-Triazol-1-yl)methyl)-3-(2-(dimethylamino)
ethyl)-1H-indol-1-yl)-4-(5-((1H-1,2,4-triazol-1-yl)methyl)-3-(2-(dimethylamino)ethyl)-1H-indol-2-yl)-N,N-dimethylbutan-1-amine
1135479-41-21,2-Dimer IMP
129Sertraline(R)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-oneTetralone (EP IMP-F)
130Sertraline(R)-2-Hydroxy-2-phenylacetic acidIMP-E
131Sildenafil4-Ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonic acidSulfonic Acid (EP IMP-D)
132SildenafilSildenafil dimerPiperazine Dimer IMP
133Sildenafil5-[2-Hydroxy-5-(4-methyl
piperazinylsulphonyl)phenyl]1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyramidin-7-one
Hydroxy (EP IMP-C)
134Sildenafil5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazole[4,3-d]pyrimidine-7-one139756-21-1Ethoxy phenyl (ED-V) IMP
135Sildenafil5-[2-Ethoxy-5-[(4-methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-(2-methylpropyl)-7H-pyrazolo[4,3-d]pyrimidin-7-oneEP IMP-A
136Sildenafil5-(2-Hydroxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-oneO-Desethylated
Ethoxy Phenyl IMP
137Sildenafil citrate4-Ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzene-1-sulfonyl chlorideSulfonylchloride IMP
138Sumatriptan1-[3-[2-(Dimethylamino)ethyl]-2-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide545338-89-4EP IMP-A
139Sumatriptan1-[3-[2-(Dimethylamino)ethyl]-1-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]indol-5-yl]-N-methylmethanesulfonamideEP IMP-H
140SumatriptanN,N-Dimethyl-2-[5-[(methylsulphamoyl)methyl]-1H-indol-3-yl] ethanamine N-oxide212069-94-8IMP-D(N-Oxide)
141Tadalafil(6S,12aS)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]
pyrido[3,4-b]indole-1,4-dione
629652-72-8L-Tadalafil (EP IMP-B)
142Tadalafil(1R,3R)-Methyl 1-(benzo[d][1,3]
dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Chloro acetyl IMP
143Tamsulosin4-[(4-Methyl-1-Piperazinyl)methyl]-N-[4-Methyl-3-[4-(3-Pyridinyl)-2-Pyrimidinyl] chloromethyl amino] phenyl]benzamideAldehyde (EP IMP-E)
144TelmisartanTelmisartan t-Butyl Ester144702-26-1IMP
145Telmisartan3-(2'-Carboxy-biphenyl-4-ylmethyl)-7-
methyl-2-propyl-3H-benzoimidazole-5-
carboxylic acid
EP (IMP-E)
146Telmisartan2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]
methyl}phenyl)benzamide
915124IMP-F
147Telmisartan4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1Hbenzimidazol]-
1'-yl)methyl]-[1,1'-
biphenyl]-2-carbonitrile
IMP-G
148Telmisartant-Butyl 4'-bromomethyl biphenyl-2-carboxylateIMP-H
149Temazepam(Z)-7-Chloro-3-methoxy-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-oneIMP-D
150TenofovirTenofovir carbonylValgancyclovir IMP-J
151Trazodone2-(3-(4-(2-Chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneOrthotrazodone IMP
152Trazodone2-(3-(4-(4-Chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneParatrazodone
153ValacyclovirValacyclovir Impurity-P(Dimer)EP IMP-P (Dimer)
154ValgancyclovirValgancyclovir Impurity-JIMP-J
155Verapamil HCl(3,4-Dimethoxyphenyl)methanol93-03-8EP IMP-E
156Zidovudine1-((2R,5R)-Tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione50-89-5Thymidine IMP
157Zolmitriptan(S)-4-((3-(2-Aminoethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one139264-15-6Amine IMP
158Zolmitriptan(R)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)oxazolidin-2-oneR-isomer IMP
159Zolmitriptan(S)-4-((3-(2-Aminoethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one139264-17-8Amine IMP
160Zolmitriptan(S)-2-Amino-3-(4-nitrophenyl)propanoic acid906813-62-54-Nitro-L-phenylalanine IMP
161Zolmitriptan(R)-2-Amino-3-(4-nitrophenyl)propanoic acid949-99-54-Nitro-D-phenylalanine IMP
162Zolmitriptan(S)-4-((3-(2-(Methylamino)ethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one139264-35-0Desmethyl (USP RC-A) IMP
.