Formulation of Ferrous Fumarate tablets by Direct-Compression

In most developing countries, the prevalence of malnutrition and micronutrient deficiencies is high among infants and young children aged 6 to 23 months. As they grow older, the energy and nutrient contribution from complementary food becomes increasingly important for meeting daily requirements. If daily food is not meeting the whole requirements then supplements should be […]

Continue Reading

Granulation in Medicine

More than 90% of all therapeutic compounds are administered via the oral route, for which the tablet dosage form is by far the most popular. The quality of these solid oral dosage forms is governed by the physicochemical properties of the powders/granulations used in their formulation. Although direct compression of APIs (active pharmaceutical ingredients) and […]

Continue Reading

Granulation Techniques and Technologies

Granulation, a technique of particle enlargement by agglomeration, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. During the granulation process, small fine or coarse particles are converted into large agglomerates called granules. Generally, granulation commences after initial dry mixing of the necessary powder ingredients […]

Continue Reading

Functionality of directly compressible adjuvants in the formulation of tablets

Over the past century, tablet manufacturers have developed materials and processes that can produce compressed tablets containing a precise amount of an active pharmaceutical ingredient (API) at high speed and at relatively low cost. The development in the field of APIs, excipients and tableting machines during thepast decades has made tablet manufacturing a science and the tablets […]

Continue Reading